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Chloroacetyl Chloride (CAS 79-04-9): The Ultimate Guide for Chemists

Author: Helen

Oct. 02, 2026

Chloroacetyl Chloride (CAS 79-04-9) is a versatile chemical compound well-known in various industrial and laboratory applications. In this comprehensive guide, we will explore its properties, functions, and various areas of application, making it an essential reference for chemists and industry professionals.

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Overview of Chloroacetyl Chloride

Chloroacetyl Chloride (CAS 79-04-9) is an organochlorine compound that appears as a colorless to light yellow liquid with a characteristic pungent odor. This chemical is notable for its reactivity, particularly in forming acyl derivatives. It is categorized under reactive halides and is typically used for synthesizing a variety of chemical products, including agrochemicals.

Physical and Chemical Properties

Chloroacetyl Chloride boasts some distinct characteristics. It has a molecular formula of C2HClO and a molecular weight of 96.92 g/mol. The compound has a boiling point of 144 °C and a density of 1.17 g/cm³ at 20 °C. Due to its reactive nature, Chloroacetyl Chloride can readily interact with water, resulting in hydrolysis and the formation of hydrochloric acid.

Safety is a primary concern when handling this chemical, as it can cause severe irritation upon contact with skin, eyes, or respiratory pathways. Therefore, appropriate safety measures, including gloves and goggles, are essential when working with Chloroacetyl Chloride (CAS 79-04-9).

Functions and Applications

One of the most significant functions of Chloroacetyl Chloride is its role as an acylating agent in organic synthesis. It is frequently used to introduce acyl groups into various organic compounds. This characteristic makes it particularly valuable in the pharmaceutical industry for developing active pharmaceutical ingredients (APIs), including antibiotic and analgesic compounds.

In addition to its pharmaceutical applications, Chloroacetyl Chloride plays a key role in the production of agrochemicals. Its ability to form esters and amides makes it useful in synthesizing pesticides, herbicides, and fungicides. These agrochemicals not only help enhance agricultural productivity but also contribute to food security, making Chloroacetyl Chloride crucial for sustainable agriculture.

Key Industries Utilizing Chloroacetyl Chloride

Chloroacetyl Chloride (CAS 79-04-9) finds applications across several industries. Below are some notable sectors that rely on its functionality:

Pharmaceuticals

In the pharmaceutical sector, Chloroacetyl Chloride is instrumental in synthesizing various medicinal compounds. Researchers leverage its acylating properties to modify existing drugs or create new medications, contributing to advancements in health care and treatment options.

Agrochemicals

The agrochemical industry benefits enormously from Chloroacetyl Chloride's ability to produce effective and efficient chemicals for pest and disease management in crops. This compound aids in developing substances that promote healthy plant growth and combat agricultural threats, ensuring producers can meet global food demands.

Specialty Chemicals

Chloroacetyl Chloride is also employed in the production of specialty chemicals. Its versatile reactivity allows it to serve as a building block for various chemical formulations, contributing to advancements in materials science and engineering.

Conclusion

In conclusion, Chloroacetyl Chloride (CAS 79-04-9) stands out as an essential compound in the realms of chemistry and industry. Its unique properties and functions make it invaluable, particularly in organic synthesis, pharmaceuticals, and agrochemical production. By understanding and harnessing its capabilities, chemists can significantly impact multiple sectors, paving the way for innovations that benefit society as a whole. When handling this compound, adherence to safety protocols is paramount, ensuring a safe working environment while unlocking its full potential.

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